Nanobody repairs misfolded CFTR inside cells, boosting function in cystic fibrosis

A tiny antibody component could fundamentally transform the treatment of cystic fibrosis: For the first time, researchers have succeeded in developing a so-called nanobody that penetrates directly into human cells and can repair the chloride channel most commonly affected in cystic fibrosis. The innovative therapeutic approach was developed in collaboration between teams from Charité—Universitätsmedizin Berlin…

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Woman builds EpiPen cannon, because why not?

Woman builds EpiPen cannon, because why not?

Get the Popular Science daily newsletter💡 Breakthroughs, discoveries, and DIY tips sent six days a week. The PVC pipe potato gun is a staple of many science-oriented (and frequently unsupervised) childhoods. There are plenty of variations to that starchy shooter, but the basic elements are invariably the same: load a potato inside the pipe barrel,…

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NBA Playoffs future odds, analysis: Where can you find the first-round value plays?

We’ve already witnessed the marvel that is the NBA playoff product compared to its often lackluster regular-season counterpart. We’re seeing every possession contested, rebounds fought for, players fighting through physical ailments and other competition-driven attributes to come to life when the pros play as if the outcome means something. Of course, that’s because it does….

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