WASHINGTON — Federal health officials issued a warning Tuesday over misleading statements made by biotech billionaire Dr. Patrick Soon-Shiong, who recently told podcast listeners that his company’s bladder cancer drug may be able to treat, cure or even prevent other types of cancers. The warning letter from the Food and Drug Administration takes issue with…
Colonies of bacterial cells under a microscope. The blue colony is expressing the synthetic genome; the white colonies are Mycoplasma capricolum cells that survived the mitomycin C treatment Nacyra Assad-Garcia A living, synthetic cell has been made by transplanting a complete genome into a dead bacterium, bringing it back to life. The breakthrough could help…
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This is a summary of: Xu, S. et al. Sustained nitric oxide production by engineered E. coli remodels the tumor microenvironment and potentiates immunotherapy. Nat. Biotechnol. https://doi.org/10.1038/s41587-026-03054-y (2026). Source: Read Full Article
Bridge RNA-guided recombinases, which originate from the IS110 family of bacterial insertion sequence elements, show promise as programmable systems for genome editing. However, most work so far has been done in bacteria. Writing in Science, Pelea et al. provide insights into a bridge recombinase that can edit human cells. Bridge recombinases act as editors by…
Nature Biotechnology, Published online: 11 March 2026; doi:10.1038/s41587-026-03047-x A lysosomal barcoding strategy to quantify endosomal escape of nucleic acids in vivo assesses the performance of branched ionizable lipids for potent liver delivery. Source: Read Full Article
Nature Biotechnology, Published online: 10 March 2026; doi:10.1038/s41587-026-03069-5 Deep B cell depletion is delivering transformative clinical results in autoimmune diseases. Dealmakers are wagering on the best tools for the job. Source: Read Full Article
