Alcohol-Related Liver Disease May Be More Common Than We Think

Alcohol-Related Liver Disease May Be More Common Than We Think

Alcohol underreporting — mainly due to recall bias or concerns about social stigma during clinical assessments — may lead to misclassification of patients with significant alcohol exposure. After adjusting for underreporting of alcohol intake, the prevalence of metabolic dysfunction-associated alcohol-related liver disease and alcohol-related liver disease doubled over a 35-year period. Binge drinking was the…

Read More

Synthetic lethality between RB-loss and E2F3 inhibition in small cell cancers targeted by pyrimidine synthesis blockade

Proceedings of the National Academy of Sciences, Volume 123, Issue 12, March 2026. <br/>SignificanceThe synthetic lethality of E2F3 inactivation in RB-deficient small cell cancer cells is established. E2F3 dependency is shared across RB-deficient cells originating from multiple tissues. The requirement for E2F3 in RB-deficient small cell … Source: Read Full Article

Read More
H.E.R. Stars in DreamWorks Movie

H.E.R. Stars in DreamWorks Movie

Dreamworks Animation has released the first trailer for its upcoming animated feature “Forgotten Island.” Set in the 1990s, H.E.R and Liza Soberano voice Jo and Raissa, two best friends who, post high-school, are about to go their separate ways. As they celebrate their last night together by eating junk food and singing karaoke, the pair…

Read More
Getting Ready for Agentic AI

Getting Ready for Agentic AI

An HBR Executive Live conversation with Pinterest CEO Bill Ready. by Adi Ignatius March 25, 2026 What if social media didn’t have to run on outrage to succeed? That’s a question on the mind of Bill Ready, CEO of Pinterest, who is on a mission to reorient the platform away from the attention-maximizing algorithms that…

Read More