Imagination Isn’t Just Memory Replay — Your Brain Rebuilds It From Scratch

Your imagination might feel like a mental replay button, conjuring images, sounds, and sensations from memory — but new research suggests something far more complex is happening behind the scenes. Rather than simply reactivating the brain’s sensory centers, imagination appears to be constructed in higher-level brain systems that organize meaning and language. Published in Neuron,…

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Courtney Love and Billy Corgan Still Hate Kim Gordon

The enemy of my enemy is also my enemy. Photo-Illustration: Mark Mainz/Getty Images;Robin Marchant/Getty Images for Vulture Courtney Love and Billy Corgan have been friends, enemies, lovers, and everything in between. But throughout their tumultuous relationship, they’ve always been able to agree on one thing: hating Kim Gordon. Love guested on Corgan’s podcast, The Magnificent…

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UFC Vegas 114 weigh-in results: 14 fights set

Blazers fined $100K, 2 executives suspended for contact with draft-ineligible player in 2023

The Portland Trail Blazers were fined $100,000 by the NBA on Wednesday for violating the league’s rules around contact with draft-ineligible players in 2023, the league announced. Blazers assistant general managers Sergi Oliva and Mike Schmitz were also suspended for two weeks without pay. The offenses reportedly occurred during the team’s scouting of Blazers center…

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New TYK2 Inhibitors for Psoriasis Achieve High Clearance Rates in Randomized Trials

New TYK2 Inhibitors for Psoriasis Achieve High Clearance Rates in Randomized Trials

DENVER — Two drug candidates to expand oral therapy options for psoriasis had similar and consistent performances in separate phase III clinical trials reported here. The allosteric TYK2 inhibitor zasocitinib achieved at least 75% improvement in the psoriasis area and severity index (PASI 75) and physician-rated clear or almost clear skin (physician global assessment [PGA]…

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8 hot, new, really real L.A. wellness trends

Millions of Angelenos flock to the newest, most luxurious and financially-aggressive pseudosciences in the name of health. Wellness is so intrinsic to our identity it raises the question: Have you had a vitamin aloe serenity scrub under a glowing red light contour mask using a triple-hydration oxygenator submerged in a vitamin C longevity mist inside…

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