No Prostate Cancer Survival Benefit With More Extensive Lymph Node Assessment

No Prostate Cancer Survival Benefit With More Extensive Lymph Node Assessment

WASHINGTON — Extended pelvic lymph node dissection (ePLND) after radical prostatectomy failed to improve survival in intermediate- and high-risk prostate cancer over standard lymphadenectomy, long-term follow-up from a randomized trial showed. After a median follow-up of almost 11 years, more extensive lymph node assessment did not significantly improve any survival outcome in the overall patient…

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Undiagnosed ADHD May Be Tied to Car Crash Injuries in Adults

Undiagnosed ADHD May Be Tied to Car Crash Injuries in Adults

Undetected attention deficit-hyperactivity disorder (ADHD) was not uncommon among adults hospitalized after traffic accidents, according to a cross-sectional study from the Dominican Republic. Among 95 adults admitted for traffic-related injuries without a prior diagnosis, more than a third (34.7%) screened positive on the Adult ADHD Self-Report Scale, reported Amanda Abreu, MD, of the Universidad Iberoamericana…

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Low-Dose Buprenorphine Enhanced Ketamine's Antisuicidal Effects in Major Depression

Low-Dose Buprenorphine Enhanced Ketamine’s Antisuicidal Effects in Major Depression

Low-dose buprenorphine significantly enhanced the antisuicidal effects of a single infusion of ketamine in patients with suicidal ideation and major depressive disorder (MDD), a randomized trial showed. Among 45 patients who received ketamine, Scale for Suicide Ideation (SSI) total scores significantly decreased from days 1 to 31 for those who received buprenorphine and those who…

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