Oklahoma vs. Colorado prediction, odds, spread, time: 2026 College Basketball Crown tournament picks from proven model

A spot in the 2026 College Basketball Crown tournament semifinals is on the line when the Oklahoma Sooners take on the Colorado Buffaloes on Wednesday. The Sooners (19-15) were the first team left out of the NCAA tournament and lost to Arkansas by three points in the SEC tournament. The Buffaloes (17-15) started the season 12-3 before Big 12 play, where Colorado finished 7-12. The Sooners have won seven of their last eight games, while the Buffaloes have lost two of their last three.

Tipoff from the MGM Grand Garden Arena in Paradise, Nevada, is set for 8 p.m. ET. The Sooners are 9.5-point favorites in the latest Oklahoma vs. Colorado odds, while the over/under for total points scored is 163.5. Before making any Colorado vs. Oklahoma picks, check out the Oklahoma vs. Colorado predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times. It enters the week of the 2026 Final Four on a sizzling 11-1 run on its top-rated over/under college basketball picks dating back to last season, and is on a 28-22 run on top-rated CBB side picks.

Now, the model has simulated Oklahoma vs. Colorado 10,000 times and just revealed its college basketball picks and predictions. You can head to SportsLine now to see the model’s picks. Here are several college basketball odds and college basketball lines for Colorado vs. Oklahoma:

Top Oklahoma vs. Colorado predictions

After 10,000 simulations of Oklahoma vs. Colorado, SportsLine’s model is going Under on the total (165.5 points). The Under hit in Oklahoma’s last two games. The total has gone under in four of the Buffaloes’ last six games against the Sooners. The total has gone under in five of Colorado’s last five games played on a Wednesday.

The model projects the Sooners to have just four players to score in double digits, led by Nijel Pack, who is projected to score 18.5 points. The Buffaloes are expected to be led by Barrington Hargress, who is projected to score 16.5 points, one of four players in double figures. The model is projecting 161 combined points as the Under clears in 65% of simulations. You can get the spread pick at SportsLine.

How to make Oklahoma vs. Colorado picks

Now, the model simulated every possession of Oklahoma vs. Colorado 10,000 times and says one side of the spread hits more than 60% of the time. You can only see that pick at SportsLine.

So who wins Oklahoma vs. Colorado, and which side of the spread hits more than 60% of the time? Visit SportsLine now to see which side of the Oklahoma vs. Colorado spread to back, all from the advanced model that just simulated this game 10,000 times, and find out.