Estradiol Patch Matches LHRH Agonists for Locally Advanced Prostate Cancer

Estradiol Patch Matches LHRH Agonists for Locally Advanced Prostate Cancer

Transdermal estradiol patches and LHRH agonists led to similar metastasis-free and overall survival in locally advanced prostate cancer. Estradiol was associated with substantially lower incidence of hot flashes but substantially more gynecomastia. Unlike oral estrogen, transdermal estradiol avoids first-pass hepatic metabolism, lowering the risk of thromboembolic cardiovascular complications. Transdermal estradiol for locally advanced prostate cancer…

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RSV shots for babies under FDA review despite evidence of safety : NPR

An electron microscope image provided by the National Institutes of Health shows human respiratory syncytial virus virions, colorized blue, and antibodies against an RSV protein, colorized yellow. AP/National Institute of Allergy and Infectious Diseases, NIH hide caption toggle caption AP/National Institute of Allergy and Infectious Diseases, NIH Health and Human Services Secretary Robert F. Kennedy…

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FDA Approves New Drug Combo for Tough-to-Treat Ovarian Cancer

FDA Approves New Drug Combo for Tough-to-Treat Ovarian Cancer

The FDA approved relacorilant (Lifyorli) in combination with nab-paclitaxel (Abraxane) for the treatment of adults with platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer. The combination of the selective glucocorticoid receptor antagonist and chemotherapy drug is indicated for patients who have received one to three prior lines of therapy, at least one of which…

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ADHD drug may reduce later risk of psychotic disorders, study finds

A large, new study found that the stimulant methylphenidate, such as the drugs Ritalin and Concerta, may lower the risk of psychosis when prescribed to younger children with ADHD. Children with attention-deficit/hyperactivity disorder have been identified to be at greater risk of developing psychotic conditions such as bipolar or schizophrenia, compared with neurotypical kids. Some…

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Kent meningitis outbreak prompts rush for routine vaccinations in England | Vaccines and immunisation

Kent meningitis outbreak prompts rush for routine vaccinations in England | Vaccines and immunisation

School immunisation services and pharmacies are reporting surging demand for routine vaccinations after the Kent meningitis outbreak in which two teenagers died. Thousands of teenagers across England have booked or received jabs in past fortnight against the A, C, W and Y strains of meningitis (MenACWY), and diphtheria, polio and tetanus (Td/IPV). Experts said the…

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